DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

PacBio has announced plans to enhance its methylation detection capabilities in HiFi sequencing by licensing advanced methods from Professor Dennis Lo and his team at The Chinese University of Hong ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

Cornell (NY, USA) researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune ...

Ancient DNA (aDNA) research, or paleogenomics, extracts and analyzes genetic material from the remains of ancient organisms, including humans, animals, and plants. Due to its age and exposure to ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

OXFORD, England, & LOS ANGELES--(BUSINESS WIRE)--Oxford Nanopore Technologies, the company behind a new generation of molecular sensing technology based on nanopores, and Plasmidsaurus, the LA-based ...

Transcriptomic Predictors of Survival for Palbociclib + Endocrine Therapy Versus Capecitabine in Aromatase Inhibitor–Resistant Breast Cancer From the GEICAM/2013-02 PEARL Trial Our findings revealed a ...