Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...

Researchers used spatial transcriptomics to map gene expression in developing wheat spikes at single-cell resolution.

The last two weeks have been packed with collaborations for unveiling innovative products and kick-starting prosperous partnerships. From quantifying His-tagged proteins and characterizing mutations ...

From startups to giants in pharma and tools, the use of spatial biology is growing in importance in drug discovery. LatchBio, a four-year-old San Francisco builder of software and data infrastructure ...

T cells sit at the center of modern immunotherapy, yet many of the rules that govern their activation, differentiation, dysfunction (e.g., exhaustion), and ...